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Azithromycin is used to treat certain infections caused by bacteria, such as bronchitis; pneumonia; sexually transmitted diseases (STD); and infections of the ears, lungs, skin, and throat. Azithromycin is in a class of medications called macrolide antibiotics. It works by stopping the growth of bacteria. Antibiotics will not work for colds, flu, or other viral infections. Less

Azithromycin is used to treat certain infections caused by bacteria, such as bronchitis; pneumonia; sexually transmitted diseases (STD); and infections of the ears, lungs, skin, and throat. Azithromycin is in a class of medications called macrolide antibiotics. It works by stopping the growth of bacteria. Antibiotics will not work for colds, flu, or other viral infections. Less

Lysodren 500 mg, 100 Tablets Lysodren (Mitotane) is used to treat pituitary- dependent hyperadrenocortic ism (Cushing's Disease) and adrenal tumors). Lysodren Miotane Prescriber Highlights - Adrenal cytoxic agent used for medical treatment of pituitary- dependent hy- peradrencorticism Caution: pregnancy, diabetes, and preexisting renal or hepatic disease Adverse Effects: Lethargy, ataxia, wekness, anorexia, vomiting, and/or diarrhea; liver changes possible. Relapses are not uncommon All dogs receiving mitotane therapy should receive additional glucocorticoid supplementation if undergoing a stress (e.g., surgery, trauma, acute illness) Monitoring is mandatorty Avoid human exposure Drug interactions Chemistry Mitotane, also commonly known in veterinary medicine as DDD, is structuarally related to the infamous insecticide, chlorophenothane (DDT). It occurs as a white, crystalline powder with slightly aromatic odor. It is practically insoluble in water and soluble in alcohol. Pharmacology While mitotane is considered an adrenal cytotoxic agent, it apparently can also inhibit adrenocortical function without causing cell destruction. the exact mechan- nisms of action for these are not clearly understood. In dogs with pituitary- dependent hyperadrenocortic ism (PDH), mitotane has been dem- onstrated to cause severe, progressive necrosis of the zona fasciculata and zona reticularis . These effects occur quite rapidly (usually within 5-10 days of starting therapy). It has been stated that mitotane spares the zona glomerulosa and therefore aldosterone synthesis is un- affected. This is only partially true, as the zona glomerulosa may also be affected by mi- totane therapy, but it is uncommon for clinically significant effects on aldosterone produc- tion to be noted with therapy. Uses/Indications Inveterinary medicine, mitotane is used primarily for the medical treatment of pituitary- dependent hyperadrenocortic ism (PDH), principally in the dog. It has also been used for the palliative treatment of adrenal carcinorma in humans and dogs. Contraindications /Precautions Mitotane is contraindicated in patients known to be hy- persensitive to it. Patients with concurrent diabetes mellitus may have rapidly changing insulin requirements during the initial treatment period. these animals should be closely monitored until they are clinically stable. Dogs with preexisting renal or hepatic disease should receive the drug with caution and with more intense monitoring. some clinicians recommend giving prednisolone at 0.2 mg/kg/day during the initial treatment period (0.4 mg/kg/day to diabetic dogs) to reduce the potential for side effects from acute endogenous steroid withdrawal. Other clinicians have argued that routinely administering steroids masks the clinical markers that signify when the endpoint of ther- apy has been reached and must be withdrawn 2-3 days before ACTH stimulation tests can be done. Since in adequately observed patients, adverse effects requiring glucocor Less

Prednisone 20 mg, 500 Tablets Prednisone is used in the treatment of many disease processes including adrenal insufficiency, arthritis, lupus, allergies, asthma, dermatitis, blood and skin disorders. New Page 1 Prednisone 20 mg, 500 Tablets Prednisone is a synthetic corticosteroid used for many conditions.nbsp; Its anti- inflammatory activity is approximately four times that of hydrocortisone. Corticosteroids are extremely effective anti- inflammatory drugs because they affect the inflammatory process at so many different levels. Prednisone is rapidly converted to prednisolone in the liver and in most instances, these drugs are considered to be roughly equivalent.nbsp; Prednisone may be given by injection, orally or topically. Dogs and Cats:nbsp; Prednisone is used for a wide variety of conditions in both dogs and cats. It may be used in emergency situations including, anaphylactic reactions, spinal chord trauma, and many forms of shock. It is used in the management and treatment of immune mediated disease such as immune mediated hemolytic anemia, or thombocytopenia: many CNS disorders: some neoplasia: dermatologic diseases: allergic reactions such as asthma, hives, and itching: inflammatory orthopedic diseases: endocrine disorders including Addison's: respiratory disease with an inflammatory component, inflammatory bowel diseases and many other conditions.nbsp; Cats may require higher doses than dogs in order to achieve clinical response, but they are less likely to develop adverse side effects. Horses:nbsp; Prednisone is given systemically to decrease inflammatory and immune responses. For years it was used orally to treat Chronic Obstructive Pulmonary Disease (COPD), and other allergic or immune-mediated disorders. Recent studies show that horses do not absorb oral prednisone, but they do absorb oral prednisolone. Other corticosteroids are preferred for intra-articular use. Side Effects: Systemic side effects to corticosteroids are generally dependent on dose and duration of treatment. Short-term use of prednisone is unlikely to cause adverse effects. Adverse effects are more common in animals on immunosuppressive doses.nbsp; Side effects seen in dogs include polyuria, polydipsia, polyphagia, poor haircoat, GI disturbance, diarrhea, vomiting, weight gain, GI ulceration, pancreatitis, lipidemia, elevated liver enzymes, diabetes mellitus, muscle wasting, and possible behavioral changes.nbsp; Polyuria, polydipsia, polyphagia may be seen in dogs even on short-term therapy.nbsp; Although cats are less likely to develop side effects than dogs, occasionally polyuria, polydipsia, polyphagia, weight gain, GI disturbances and behavioral changes occur.nbsp; Corticosteroids can cause or worsen gastric ulcers. Precautions: nbsp; Chronic or inappropriate use of corticosteroids can cause life threatening hormonal and metabolic changes.nbsp; Adverse effects due to corticosteroid treatment usually occur with long-term administration of the drug, especially when h Less