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The Cannabinoid Receptors

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Walmart.com The Cannabinoid Receptors
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endoCANNABINOIDS : Actions at...

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Walmart.com endoCANNABINOIDS : Actions at Non-CB1/CB2 Cannabinoid Receptors
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This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their atypical cannabinoid signalling. This book provides insight into the potential medical application of cannabinoids and their therapeutic development for the treatment of human disease.
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Functional Synthetic Receptors

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Walmart.com Functional Synthetic Receptors
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A timely overview of this rapidly- expanding topic, covering the most important classes of compounds and incorporating the latest literature. With its application- oriented approach, this book is the first to emphasize current and potential applications, extending to such fields as materials science, bioorganic chemistry, medicinal chemistry, and organic synthesis. In the biological context in particular, the book clarifies which receptor systems work well in water or better under physiological conditions.From the contents: * Amino Acid, Peptid and Protein Receptors* Carbohydrate Receptors* Ammonium, Amidinium and Guanidinium Receptors* Anion Receptors* Molecular Capsules and Self Assembly* Dynamic Combinatorial Libraries based on Molecular Recognition * Molecular Machines * Self-... Less
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Toll-Like Receptors: Roles in...

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Walmart.com Toll-Like Receptors: Roles in Infection and Neuropathology
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Mammalian Toll-like receptors (TLRs) were first identified in 1997 based on their homology with Drosophila Toll, which mediates innate immunity in the fly. In recent years, the number of studies describing TLR expression and function in the nervous system has been increasing steadily and expanding beyond their traditional roles in infectious diseases to neurodegenerative disorders and injury. Interest in the field serves as the impetus for this volume in the Current Topics in Microbiology and Immunology series entitled Toll-like receptors: Roles in Infection and Neuropathology. The first five chapters highlight more traditional roles for TLRs in infectious diseases of the CNS. The second half of the volume discusses recently emerging roles for TLRs in non-infectious neurodegenerative ... Less
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Fc Receptors

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Walmart.com Fc Receptors
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Hardcover, Springer Verlag, 2014, ISBN13 9783319079103, ISBN10 3319079107
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Chemokine Receptors in Cancer

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Walmart.com Chemokine Receptors in Cancer
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Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation or injury. In humans, there are approximately 45 chemokines that bind to 19 G-protein-coupled receptors. In addition to mediating cellular migration, chemokines have now been shown to affect many cellular functions including survival, adhesion, invasion, proliferation, and to regulate circulating chemokine levels. Although chemokine receptors were first described on leukocytes, it is now appreciated that chemokine receptors are also expressed by many other cells including endothelial and epithelial cells. Since the first description of chemokine receptors on malignant cells in 2001, an extensive... Less
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Prostacyclin and Its Receptors

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Walmart.com Prostacyclin and Its Receptors
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In addition to its well known anti-platelet and hypotensive properties, prostacyclin activates neuronal receptors in the central, enteric and sensory nervous systems. This volume discusses the properties of prostacyclin receptors in the cardiovascular and nervous systems, as well as in cells involved in inflammatory reactions. The chemistry and pharmacology of prostacyclin mimetics are also explored, higlighting their therapeutic value.
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Synthetic Receptors for...

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Walmart.com Synthetic Receptors for Biomolecules: Design Principles and Applications
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Hardcover, Royal Society of Chemistry, 2015, ISBN13 9781849739719, ISBN10 1849739714
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Negative Co-Receptors and...

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Walmart.com Negative Co-Receptors and Ligands
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Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules.
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Nuclear Receptors: Current...

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Walmart.com Nuclear Receptors: Current Concepts and Future Challenges
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In 1980 a case of myxedema was treated in Lisbon by the implantation of a sheep thyroid gland with the immediate improvement in the patient s condition. A few years later, medications for the then ill-explained condition of the menopause included table
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Methods for the Discovery and...

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Walmart.com Methods for the Discovery and Characterization of G Protein-Coupled Receptors
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The goal of the characterization and discovery of G protein-coupled receptors, arguably the most important class of signaling molecules in humans and other vertebrates, has spawned numerous vital methodologies. In Methods for the Discovery and Characterization of G Protein-Coupled Receptors, experts in the field present the very latest on the methods and technology used to characterize and discover novel mechanisms of GPCRs which, in many cases, can be used directly to design experiments for the reader s particular GPCR of interest and their specific avenue of investigation. Divided into four convenient sections, this detailed volume covers GPCRs in the genome, trafficking of GPCRs, GPCRs on the membrane, as well as the regulation of these key receptors. Chapters also feature an important... Less
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Genomics of Pattern...

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Walmart.com Genomics of Pattern Recognition Receptors: Applications in Oncology and Cardiovascular Diseases
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This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.--
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BLyS Ligands and Receptors

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Walmart.com BLyS Ligands and Receptors
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This volume will center on the BLyS(BAFF) family of ligands and receptors. It will be divided into sections based on topics covering both basic and translational/cli nical aspects of this molecular family's biology. It will focus heavily the BLyS family's role in the differentiation, selection, and regulation of primary and antigen- experienced B cells. Additional sections will cover clinical aspects of this family, including its association with autoimmunity and neoplasia, current thinking about the mechanistic basis for these associations, and the potential of BLyS family members as therapeutic targets. In addition, how BLyS family members play roles in other cell types may be included.
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Orphan G Protein-Coupled...

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Walmart.com Orphan G Protein-Coupled Receptors and Novel Neuropeptides
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Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms. The chapters of this book review the latest research in the field, most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is set not only on their discovery but also on their functional... Less
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Chemokine Receptors and...

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Walmart.com Chemokine Receptors and NeuroAIDS: Beyond Co-Receptor Function and Links to Other Neuropathologies
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Chemokine Receptors and NeuroAIDS: Beyond the Co-receptor Function and Links to Other Neuropathologies focuses on unresolved or emerging issues concerning the role of chemokine receptors in neuronal injury and HIV neuropathology, including their ability to regulate fundamental neuronal and glial functions and their role in neurovirulence and neurotoxicity. Although the importance of these molecules in the CNS physiology and pathology is now apparent, these issues are still matter of debate, and further research is required to design effective pharmacological agents that specifically target the brain chemokine system without major side effects. To this end, specific topics have been selected and are reviewed by international experts within the basic science/medical community. This book... Less
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Diverse Roles of Integrin...

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Walmart.com Diverse Roles of Integrin Receptors in Articular Cartilage
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Integrins are heterodimeric integral membrane proteins made up of a and subunits. At least 18 a and 8 subunit genes have been described in mammals. Integrin family members are plasma membrane receptors involved in cell adhesion and active as intra- and extracellular signalling molecules in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic spread of tumor cells. Integrin beta 1 (1-integrin) the protein encoded by the ITGB1 gene (also known as CD29 and VLAB) is a multi-functional protein involved in cell-matrix adhesion, cell signalling, cellular defense, cell adhesion, protein binding, protein heterodimerizatio n and receptor- mediated activity. It is highly expressed in the human body (17.4 times higher than the average gene in the... Less
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Diversity and Functions of...

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Walmart.com Diversity and Functions of Gaba Receptors: A Tribute to Hanns M?hler
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Hardcover, Academic Pr, 2015, ISBN13 9780128026588, ISBN10 0128026588
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Microscopic view of taste...

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Walmart.com Microscopic view of taste buds on tongue Taste buds contain the receptors for taste They are located around the small structures on the upper surface of the tongue soft palate upper esophagus Poster P
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Microscopic view of taste buds on tongue. was reproduced on Premium Heavy Stock Paper which captures all of the vivid colors and details of the original. The overall paper size is inches and the image size is inches. This print is ready for hanging or framing.Brand New and Rolled and ready for display or framingPrint Title: Microscopic view of taste buds on tongue.Paper Size: inchesPublisher: StockTrek ImagesArtist: Stocktrek Images
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Microscopic view of taste...

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Walmart.com Microscopic view of taste buds on tongue Taste buds contain the receptors for taste They are located around the small structures on the upper surface of the tongue soft palate upper esophagus Poster P
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Microscopic view of taste buds on tongue. was reproduced on Premium Heavy Stock Paper which captures all of the vivid colors and details of the original. The overall paper size is inches and the image size is inches. This print is ready for hanging or framing.Brand New and Rolled and ready for display or framingPrint Title: Microscopic view of taste buds on tongue.Paper Size: inchesPublisher: StockTrek ImagesArtist: Stocktrek Images
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